Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognise her kids.

When a high school coach is faced with a debilitating illness, Dr. Wolf must help his patient reconnect with her body before it's too late.

A member of a biker gang seeks out Wolf's help as he grapples with life-threatening memory loss. The interns are tasked to help a young girl struggling with mysterious seizures.

When a bloody bride stumbles into Bronx General, Wolf goes to extreme measures in a race against the clock to save her and her missing husband.

Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.